Main Clinical F indings in Five P atients With ATLL Patient Age Sex Race Origin ’ Leukocytes Ix 109 / Liter ) Lymphocytes Ix

نویسندگان

  • Frank Miedema
  • Fokke G. Terpstra
  • Jan W. Smit
  • Simon Daenen
  • Wim Gerrits
  • Daniel Catovsky
  • Melvyn F. Greaves
  • Cornelis J.M. Melief
چکیده

The neoplastic T cells from five patients with adult T cell lymphoma/leukemia (ATIL). born in the Caribbean. were studied with respect to immunoregulatory activity on pokeweed mitogen (PWM) driven immunoglobulin (Ig) synthesis as well as surface-marker phenotypes with monoclonal antibodies. The neoplastic T cells in all patients had an OKT1 4 8 11 M1 Ii 3A1 phenotype. but differed in the reactivity with 0KT3. None of the patients cells exerted helper activity on PWM-induced Ig synthesis. The

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تاریخ انتشار 2005